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Article

Role of key genetic mutations on increasing migration of brain cancer cells through confinement.

Biomedical microdevices - 1 Sept 2017

Bui Loan, Bhuiyan Sayem H, Hendrick Alissa, Chuong Cheng-Jen, Kim Young-Tae

Abstract excerpt

Uncontrolled invasive cancer cell migration is among the major challenges for the treatment and management of brain cancer. Although the genetic profiles of brain cancer cells have been well characterized, the relationship between the genetic mutations and the cells' mobility has not been clearly understood. In this study, using microfluidic devices that provide a wide range of physical confinements from...

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Source

Identifiers

PMID: 28620782
DOI: 10.1007/s10544-017-0197-9

Genes

BRAF
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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