Article

CCN4 shifts melanoma cells from a fragile proliferative state to a resilient metastatic state

2018-12-06

Abstract excerpt

<h4>ABSTRACT</h4> While deregulated intracellular signaling initiates melanoma, intercellular crosstalk within the tumor microenvironment, often coordinated by soluble factors, is essential for melanoma progression and metastasis. One such secreted matricellular protein, cellular communication network factor 4 (CCN4), stimulates metastasis in other malignancies. Here, we report that CCN4 expression is associated...

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Literature Corpus work: bf5ee457-7dc4-5bdf-8d73-1d684f55344a
DOI: 10.1101/487751

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