Article

Head-to-head comparison of CCN4, DNMT3A, PTPN11, and SPARC as suppressors of anti-tumor immunity

2022-04-01

Abstract excerpt

<h4>Background</h4> Effective communication between innate and adaptive immunity is essential for mounting an effective antitumor immune response. Emergent cancer cells likely secrete factors that inhibit this communication. To identify such factors, we applied an in vitro workflow that coupled a functional assay with proteomics to a syngeneic mouse model of melanoma known to be resistant to immunotherapies. Coll...

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Literature Corpus work: 7426c829-08a9-5527-9839-fcf106498afb
DOI: 10.1101/2022.04.01.486749

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