Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1

13 Nov 2006

Abstract excerpt

Melanocytes reside within the basal layer of the human epidermis, where they attach to the basement membrane and replicate at a rate proportionate to that of keratinocytes, maintaining a lifelong stable ratio. In this study, we report that coculturing melanocytes with keratinocytes up-regulated CCN3, a matricellular protein that we subsequently found to be critical for the spatial localization of melanocytes to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Connective Tissue Growth Factor Research
Share to melanin and skin pigmentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17101694
DOI: 10.1083/jcb.200602132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1PMID 17101694Read ↗

Spatial-temporal modulation of CCN proteins during wound healing in human skin in vivoSemantic proximity Read ↗

Crosstalk in skin: melanocytes, keratinocytes, stem cells, and melanomaSemantic proximity Read ↗

Keratinocyte cadherin desmoglein 1 controls melanocyte behavior through paracrine signalingSemantic proximity Read ↗

Mesenchymal–epithelial interactions in the skinSemantic proximity Read ↗

Keratinocyte desmoglein 1 regulates the epidermal microenvironment and tanning responseSemantic proximity Read ↗

CCN4 shifts melanoma cells from a fragile proliferative state to a resilient metastatic stateSemantic proximity Read ↗

Inactivation of kindlin-3 increases human melanoma aggressiveness through the collagen-activated tyrosine kinase receptor DDR1Semantic proximity Read ↗

KRT5 mutation regulate melanin metabolism through notch signalling pathway between keratinocytes and melanocytes.Semantic proximity Read ↗

Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal AgingSemantic proximity Read ↗

The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and AngiogenesisSemantic proximity Read ↗

Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis.Semantic proximity Read ↗

A Skin-depth Analysis of Integrins: Role of the Integrin Network in Health and DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.