Article

SomaticSignatures: Inferring Mutational Signatures from Single Nucleotide Variants

2014-10-24

Abstract excerpt

Mutational signatures are patterns in the occurrence of somatic single nucleotide variants (SNVs) that can reflect underlying mutational processes. The SomaticSignatures package provides flexible, interoperable, and easy-to-use tools that identify such signatures in cancer sequencing data. It facilitates large-scale, cross-dataset estimation of mutational signatures, implements existing methods for pattern decompo...

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Literature Corpus work: bece3b21-7f76-578c-a1e2-dcd2f83b66b8
DOI: 10.1101/010686

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