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Article

Identification of mutational signatures active in individual tumors

2017-09-17

Abstract excerpt

The mutational processes responsible for the somatic mutations observed in tumor samples can significantly vary not only between tumor types but also among the individual cancers within a tumor class. Mutational processes can be represented by so called “mutational signatures” which reflect the occurrences of base changes within their sequence contexts (i.e., in dependence on their flanking bases). We present a us...

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Identifiers and source

Literature Corpus work
2712e2db-5104-5528-afb3-3d8652d988f5
DOI
10.7287/peerj.preprints.3257v1
Open publication

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Identification of mutational signatures active in individual tumorsDOI 10.7287/peerj.preprints.3257v1
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