Article

<i>TNF</i>promoter hypomethylation is associated with mucosal inflammation in IBD and anti-TNF response

2024-02-06

Abstract excerpt

<h4>Background and aims</h4> Inflammatory Bowel Diseases (IBD) are chronic inflammatory conditions influenced heavily by environmental factors. DNA methylation is a form of epigenetic regulation linking environmental stimuli to gene expression changes and inflammation. Here, we investigated how DNA methylation of the TNF promoter differs between inflamed and uninflamed mucosa of IBD patients, including anti-TNF re...

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Literature Corpus work: beb598e1-2f57-5bec-ab88-1905e158c01e
DOI: 10.1101/2024.02.05.24302343

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