Article

TNFSF13 insufficiency disrupts human colonic epithelial cell-mediated B cell differentiation

2024-09-23

Abstract excerpt

<h4>ABSTRACT</h4> Cytokines mediating epithelial and immune cell interactions modulate mucosal healing-a process that goes awry with chronic inflammation as in inflammatory bowel disease. TNFSF13 is a cytokine important for B cell maturation and function, but roles for epithelial TNFSF13 and putative contribution to inflammatory bowel disease are poorly understood. We evaluated functional consequences of a novel...

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Literature Corpus work: 5e8b6dc2-f941-5c89-9de8-c9ce418ab3df
DOI: 10.1101/2024.09.23.614260

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