Article

Evaluation of the TLR 4 and TLR 5 genes methylation and mRNA expression in patients with Inflammatory Bowel Disease

2023-04-05

Abstract excerpt

<h4>Background: </h4> Immune system dysfunction, especially Toll-Like Receptors (TLRs), is a major factor in the pathogenesis of IBD. The functional roles of TLR 4 and TLR 5 as mediators of innate immune responses to pathogenic microbes in the gastrointestinal tract and their association with epigenetic alterations in the pathogenesis of this disease are very important. We aimed to investigate the aberrant methyla...

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Literature Corpus work: 411a89db-d80b-5071-8f41-3990f8b2ffb1
DOI: 10.21203/rs.3.rs-2769983/v1

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