Article

Dietary supplementation with PUFAs rescues the eggshell defects caused by <i>seipin</i> mutations in <i>C. elegans</i>

2020-01-23

Abstract excerpt

SEIPIN, an ER membrane protein, plays critical roles in lipid droplet (LD) formation and lipid storage. Dysfunction of SEIPIN causes a variety of human diseases, including lipodystrophy, neuropathies, and male and female infertility. However, the cellular and molecular mechanisms of SEIPIN in causing these diseases are poorly understood. To address such mechanisms, we investigated the functional roles of R01B10.6...

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Literature Corpus work: be9760a9-2f8d-5620-b3cb-3cd850ceab01
DOI: 10.1101/2020.01.23.916718

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