Article

Dietary <i>S. maltophilia</i> promotes fat storage by enhancing lipogenesis and ER-LD contacts in <i>C. elegans</i>

2020-04-30

Abstract excerpt

Dietary and symbiotic bacteria can exert powerful influence on metazoan lipid metabolism. Here, we demonstrate that feeding Caenorhabditis elegans (C. elegans) with the opportunistic pathogenic bacteria Stenotrophomonas maltophilia (S. maltophilia) retards growth and promotes excessive fat storage. Gene expression analysis reveals that dietary S. maltophilia induces a lipogenic transcriptional response that inc...

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Literature Corpus work: b91803f4-6eda-59e1-854f-948a7bfb22bd
DOI: 10.1101/2020.04.29.067793

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