Article
Genetics of Lipid-Storage Management in Caenorhabditis elegans Embryos.
Genetics - 1 Mar 2016
Schmökel Verena, Memar Nadin, Wiekenberg Anne, Trotzmüller Martin, Schnabel Ralf, Döring Frank
Abstract excerpt
Lipids play a pivotal role in embryogenesis as structural components of cellular membranes, as a source of energy, and as signaling molecules. On the basis of a collection of temperature-sensitive embryonic lethal mutants, a systematic database search, and a subsequent microscopic analysis of >300 interference RNA (RNAi)-treated/mutant worms, we identified a couple of evolutionary conserved genes associated with...
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