Article
Whole-genome RNAi screen identifies methylation-related genes influencing lipid metabolism in Caenorhabditis elegans.
Journal of genetics and genomics = Yi chuan xue bao - 20 May 2018
Zhu Xiaotong, Liu Yangli, Zhang Hong, Liu Pingsheng
Abstract excerpt
Lipid droplets (LDs) are highly conserved multifunctional cellular organelles and aberrant lipid storage in LDs can lead to many metabolic diseases. However, the molecular mechanisms governing lipid dynamic changes remain elusive, and the high-throughput screen of genes influencing LD morphology was limited by lacking specific LD marker proteins in the powerful genetic tool Caenorhabditis elegans. In this study,...
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