Article

The EDC4-XRN1 axis controls P-body dynamics to link mRNA decapping with decay

2023-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Deadenylation-dependent mRNA decapping and decay is the major cytoplasmic mRNA turnover pathway in eukaryotes. Many mRNA decapping and decay factors associate with each other via protein-protein interaction motifs. For example, the decapping enzyme DCP2 and the 5’-3’ exoribonuclease XRN1 interact with enhancer of mRNA decapping protein 4 (EDC4), a large scaffold that has been reported to stimula...

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Literature Corpus work: be7a80ce-0f19-5d2b-b730-4eaab370ca91
DOI: 10.1101/2023.03.06.531261

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