Article

Omicron’s Spike Receptor-Binding Domain Mutations Significantly Stabilize its Conformational State

2024-01-09

Abstract excerpt

The Omicron variant and its sub lineages are the only current circulating SARS-CoV-2 viruses world-wide. In this study, the conformational stability of the isolated Receptor Binding Domain (RBD) of the virus’s spike protein, which has been used for highly successful vaccines (Ref. 12), is examined in detail. The conformational stability of Omicron’s RBD over the Wild-type (WT) strain is shown to be greatly increas...

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Literature Corpus work: be6b8b03-23c4-5c9a-9685-b65a3b383942
DOI: 10.21203/rs.3.rs-3834866/v1

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