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Article

Molecular insights into the binding interactions and energetics of the omicron spike variant with hACE2 and a neutralizing antibody.

Journal of structural biology - 1 Jun 2024

Kumar Vipul, Shefrin Seyad, Sundar Durai

Abstract excerpt

The global spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) since 2019 has led to a continuous evolution of viral variants, with the latest concern being the Omicron (B.1.1.529) variant. In this study, classical molecular dynamics simulations were conducted to elucidate the biophysical aspects of the Omicron spike protein's receptor-binding domain (RBD) in its interaction with human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38494148
DOI: 10.1016/j.jsb.2024.108087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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