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Article

Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain.

Nature communications - 3 Mar 2022

Ye Gang, Liu Bin, Li Fang

Abstract excerpt

The omicron variant of SARS-CoV-2 has been spreading rapidly across the globe. The virus-surface spike protein plays a critical role in the cell entry and immune evasion of SARS-CoV-2. Here we determined the 3.0 Å cryo-EM structure of the omicron spike protein ectodomain. In contrast to the original strain of SARS-CoV-2 where the receptor-binding domain (RBD) of the spike protein takes a mixture of open...

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Share to Antibodies, Neutralizing
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Share to Cryoelectron Microscopy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Interaction Domains and Motifs

Share to Spike Glycoprotein, Coronavirus

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Source

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Identifiers

PMID: 35241675
DOI: 10.1038/s41467-022-28882-9
PMCID: PMC8894419

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