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Article

Shared genetic etiology underlying late-onset Alzheimer's disease and posttraumatic stress syndrome.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Sept 2020

Lutz Michael W, Luo Sheng, Williamson Douglas E, Chiba-Falek Ornit

Abstract excerpt

INTRODUCTION: Late-onset Alzheimer's disease (LOAD) manifests comorbid neuropsychiatric symptoms and posttraumatic stress disorder (PTSD) is associated with an increased risk for dementia in late life, suggesting the two disorders may share genetic etiologies. METHODS: We performed genetic pleiotropy analysis using LOAD and PTSD genome-wide association study (GWAS) datasets from white and African-American...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32588970
DOI: 10.1002/alz.12128
PMCID: PMC7769164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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