Article

Interactions with early-life exposures modulate polygenic risk of wheeze and asthma in preschool-aged children

2020-10-05

Abstract excerpt

<h4>Background: </h4> Asthma is a multifactorial disease with numerous associated genetic and environmental risk factors, however, gene-environment interactions are poorly understood in modulating disease risk. This study determines the polygenic effects of multiple genetic loci and interactions with environmental exposures during early infancy on risk of recurrent wheeze and asthma in pre-school aged children. <h...

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Literature Corpus work: be306559-722c-501e-abd5-8387952f7319
DOI: 10.22541/au.159986525.53189546/v2

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