Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.

doi:10.1164/rccm.200809-1436OC

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Article

Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.

American journal of respiratory and critical care medicine - 1 Feb 2009

Bisgaard Hans, Bønnelykke Klaus, Sleiman Patrick M A, Brasholt Martin, Chawes Bo, Kreiner-Møller Eskil, Stage Malene, Kim Cecilia, Tavendale Roger, Baty Florent, Pipper Christian Bressen, Palmer Colin N A, Hakonarsson Hakon

Abstract excerpt

RATIONALE: An asthma predisposition locus on chromosome 17q12-q21 has recently been replicated in different ethnic groups. OBJECTIVES: To characterize the asthma and atopy phenotypes in early childhood that associate with the 17q12-21 locus. METHODS: The single nucleotide polymorphism (SNP), rs7216389, was genotyped in 376 of 411 children from the Copenhagen Prospective Study on Asthma in Childhood (COPSAC) birth...

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PMID: 19029000
DOI: 10.1164/rccm.200809-1436OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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