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Article

Gene-environment interactions in human disease: nuisance or opportunity?

Trends in genetics : TIG - 1 Mar 2011

Ober Carole, Vercelli Donata

Abstract excerpt

Many environmental risk factors for common, complex human diseases have been revealed by epidemiologic studies, but how genotypes at specific loci modulate individual responses to environmental risk factors is largely unknown. Gene-environment interactions will be missed in genome-wide association studies and could account for some of the 'missing heritability' for these diseases. In this review, we focus on...

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Identifiers

PMID: 21216485
DOI: 10.1016/j.tig.2010.12.004
PMCID: PMC3073697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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