Genetics and Gene-Environment Interactions in Childhood and Adult Onset Asthma

Abstract excerpt

Asthma is a heterogeneous disease that results from the complex interaction between genetic factors and environmental exposures that occur at critical periods throughout life. It seems plausible to regard childhood-onset and adult-onset asthma as different entities, each with a different pathophysiology, trajectory and outcome. This review provides an overview about the role of genetics and gene-environment...