Article
A Narrative Review of Gene-Environment Interactions in Pediatric Pulmonology.
Pediatric pulmonology - 1 Mar 2026
Kelchtermans Jelte
Abstract excerpt
Genetic and environmental factors are known to shape the onset, course, and outcomes of pediatric lung disease, yet interactions between these variables are rarely considered in clinical practice. Gene-environment (GxE) interactions occur when the combined effect of a genetic variant and an environmental exposure differs from what would be expected from combining the effect of either variable alone. Considering...
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