Article
Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.
The Lancet. Respiratory medicine - 1 Jun 2019
Pividori Milton, Schoettler Nathan, Nicolae Dan L, Ober Carole, Im Hae Kyung
Abstract excerpt
BACKGROUND: Childhood-onset and adult-onset asthma differ with respect to severity and comorbidities. Whether they also differ with respect to genetic risk factors has not been previously investigated in large samples. The goals of this study were to identify shared and distinct genetic risk loci for childhood-onset and adult-onset asthma, and to identify the genes that might mediate the effects of associated...
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