Article

Methylation of Dual Specificity Phosphatase 4 Controls Cell Differentiation

2020-12-16

Abstract excerpt

A collection of signaling and epigenetic events needs to be orchestrated for normal development of hematopoietic lineages. While mitogen-activated protein (MAP) kinases (MAPKs) and multiple epigenetic modulators have been implicated in the megakaryocytic (Mk) cell differentiation, the underlying molecular mechanisms of signaling-epigenetic crosstalk remain unclear. MAPKs are in general inactivated by dual specific...

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Literature Corpus work: be2951fe-4fe7-5d7c-9087-a46183adfd04
DOI: 10.1101/2020.12.16.422727

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