Article

Dual Specificity Phosphatase 3 knockdown drives myeloid leukemia cells to differentiate into macrophages and polarize

2024-10-02

Abstract excerpt

<h4>ABSTRACT</h4> The dual-specificity phosphatase 3 (DUSP3) has been implicated in the maintenance of genomic stability, cell cycle, proliferation, and differentiation. Recently we reported an important role of the interaction between DUSP3 and nucleophosmin (NPM) proteins on the regulation of the p53 actions to maintain genomic stability. Since both p53 and NPM often have mutations related to a diverse set of l...

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Literature Corpus work: 79d34e8e-d7e1-5597-8f74-77f90205f0e2
DOI: 10.1101/2024.09.30.615030

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