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Article

Dpy30 is critical for maintaining the identity and function of adult hematopoietic stem cells.

The Journal of experimental medicine - 17 Oct 2016

Yang Zhenhua, Shah Kushani, Khodadadi-Jamayran Alireza, Jiang Hao

Abstract excerpt

As the major histone H3K4 methyltransferases in mammals, the Set1/Mll complexes play important roles in animal development and are associated with many diseases, including hematological malignancies. However, the role of the H3K4 methylation activity of these complexes in fate determination of hematopoietic stem and progenitor cells (HSCs and HPCs) remains elusive. Here, we address this question by generating a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27647347
DOI: 10.1084/jem.20160185
PMCID: PMC5068233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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