Article

PCF11 links alternative polyadenylation to formation and spontaneous regression of neuroblastoma

2018-10-10

Abstract excerpt

Diversification at the transcriptome 3’end is an important and evolutionarily conserved layer of gene regulation associated with differentiation and dedifferentiation processes. However the underlying mechanisms and functional consequences are poorly defined. Here, we identify extensive transcriptome-3’end-alterations in neuroblastoma, a tumour entity with a paucity of recurrent somatic mutations and an unusually...

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Literature Corpus work: 07d745be-dd0c-5128-a0d8-a2e5515a2789
DOI: 10.1101/426536

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