Article

Relaxed peripheral tolerance drives broad <i>de novo</i> autoreactivity in severe COVID-19

2020-10-23

Abstract excerpt

An emerging feature of COVID-19 is the identification of autoreactivity in patients with severe disease that may contribute to disease pathology, however the origin and resolution of these responses remain unclear. Previously, we identified strong extrafollicular B cell activation as a shared immune response feature between both severe COVID-19 and patients with advanced rheumatic disease. In autoimmune settings,...

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Identifiers and source

Literature Corpus work: bdb2457f-bf5e-5837-b339-a99c2c0b05f7
DOI: 10.1101/2020.10.21.20216192

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