Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cutting Edge: Distinct B Cell Repertoires Characterize Patients with Mild and Severe COVID-19

28 May 2021

Abstract excerpt

Protective immunity against COVID-19 likely depends on the production of SARS-CoV-2-specific plasma cells and memory B cells postinfection or postvaccination. Previous work has found that germinal center reactions are disrupted in severe COVID-19. This may adversely affect long-term immunity against reinfection. Consistent with an extrafollicular B cell response, patients with severe COVID-19 have elevated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34049971
DOI: 10.4049/jimmunol.2100135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cutting Edge: Distinct B Cell Repertoires Characterize Patients with Mild and Severe COVID-19PMID 34049971Read ↗

A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunitySemantic proximity Read ↗

Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19Semantic proximity Read ↗

Pandemic, epidemic, endemic: B cell repertoire analysis reveals unique anti-viral responses to SARS-CoV-2, Ebola and Respiratory Syncytial VirusSemantic proximity Read ↗

A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patientsSemantic proximity Read ↗

A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 PatientsSemantic proximity Read ↗

COVID-19 Infection Induces Substantial Memory B Cell Maturation to Non-Neutralizing Viral TargetsSemantic proximity Read ↗

Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19Semantic proximity Read ↗

Immune Features of COVID-19 Convalescent Individuals Revealed by a Single-cell RNA SequencingSemantic proximity Read ↗

Maturation and persistence of the anti-SARS-CoV-2 memory B cell responseSemantic proximity Read ↗

Heterogeneous immunological recovery trajectories revealed in post-acute COVID-19Semantic proximity Read ↗

Early Fc-effector antibody signatures impact COVID-19 disease trajectorySemantic proximity Read ↗

Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.