Article

BRCA1 mutation promotes sprouting angiogenesis in inflammatory cancer-associated fibroblast of triple-negative breast cancer

2023-09-28

Abstract excerpt

<title>Abstract</title> <p>Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with inferior outcomes owing to its low treatment response and high invasiveness. Based on abundant cancer-associated fibroblasts (CAFs) and frequent mutation of <italic>breast cancer-associated 1 (BRCA1)</italic> in TNBC, the characteristics of CAFs in TNBC patients with <italic>BRCA1</italic> mutation compared...

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Literature Corpus work: bda17d25-6f44-56ab-94ce-c61e5fa747f7
DOI: 10.21203/rs.3.rs-3291809/v1

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