Article
Vasculogenic Mimicry in Breast Cancer: Clinical Relevance and Drivers.
Cells - 12 Jul 2021
Morales-Guadarrama Gabriela, García-Becerra Rocío, Méndez-Pérez Edgar Armando, García-Quiroz Janice, Avila Euclides, Díaz Lorenza
Abstract excerpt
In solid tumors, vasculogenic mimicry (VM) is the formation of vascular structures by cancer cells, allowing to generate a channel-network able to transport blood and tumor cells. While angiogenesis is undertaken by endothelial cells, VM is assumed by cancer cells. Besides the participation of VM in tumor neovascularization, the clinical relevance of this process resides in its ability to favor metastasis and to...
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