Article

Single-cell profiling reveals the sustained immune infiltration, surveillance, and tumor heterogeneity of infiltrative BCC

2022-08-25

Abstract excerpt

<h4>Background</h4> Infiltrative basal cell carcinoma (iBCC) is a particularly aggressive subtype of BCC that tends to recur after surgery, and its progression and malignancy are closely related to its interaction with the local tumor microenvironment (TME). <h4>Methods</h4> Here, we performed single-cell RNA sequencing (scRNA-seq) from 5 patients to determine the dynamic changes of TME between iBCC and adjacent n...

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Literature Corpus work: 7a12bda6-8e57-5c48-b606-8dd4f7d12448
DOI: 10.1101/2022.08.22.22278093

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