Article

TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids

2019-12-13

Abstract excerpt

<h4>SUMMARY</h4> Telencephalic organoids generated from human pluripotent stem cells (hPSCs) are emerging as an effective system to study the distinct features of the developing human brain and the underlying causes of many neurological disorders. While progress in organoid technology has been steadily advancing, many challenges remain including rampant batch-to-batch and cell line-to-cell line variability and ir...

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Literature Corpus work: bd80c498-5ef5-57dc-82db-7cb99a2716da
DOI: 10.1101/2019.12.13.875773

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