Article

Reconstitution of Human Brain Cell Diversity in Organoids via Four Protocols

2024-11-17

Abstract excerpt

Human brain organoids are powerful in vitro models for brain development and disease. However, their variability can complicate use in biomedical research and drug discovery. Both the specific protocol as well as the pluripotent starting cell line influence organoid variability and can result in incomplete representation of brain cell types in an organoid experiment. Here, we systematically analyze the cellular a...

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Literature Corpus work: d9e28c58-cdd0-513a-a54c-c9fb8f2c6df4
DOI: 10.1101/2024.11.15.623576

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