Article

Cross-site reproducibility of human cortical organoids reveals consistent cell type composition and architecture

2023-07-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background:</h4> Reproducibility of human cortical organoid (hCO) phenotypes remains a concern for modeling neurodevelopmental disorders. While guided hCO protocols reproducibly generate cortical cell types in multiple cell lines at one site, variability across sites using a harmonized protocol has not yet been evaluated. We present an hCO cross-site reproducibility study examining multiple...

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Literature Corpus work: 8832e859-7b0d-55da-a61b-58d276f5360e
DOI: 10.1101/2023.07.28.550873

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