Article

Deciphering Brain Organoids Heterogeneity by Identifying Key Quality Determinants

2025-01-13

Abstract excerpt

Brain organoids derived from human pluripotent stem cells (hPSCs) hold immense potential for modeling neurodevelopmental processes and disorders. However, their experimental variability and undefined organoid selection criteria for analysis hinder reproducibility. As part of the Bavarian ForInter consortium, we generated 72 brain organoids from distinct hPSC lines. We conducted a comprehensive analysis of their mo...

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Literature Corpus work: d26da90b-42a7-5b6b-b3b2-d78464edb867
DOI: 10.1101/2025.01.13.632763

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