Article

Engineering autologous ossicles for the personalized modeling of acute myeloid leukemia

2026-04-17

Abstract excerpt

Acute Myeloid Leukemia (AML) is the most lethal hematological malignancy in adults and is characterized by significant genetic and cytogenetic heterogeneity. This diversity drives substantial patient-to-patient variability in disease progression and therapeutic response. Increasing evidence indicates that bone marrow mesenchymal stem/stromal cells (MSCs) play a critical role in AML emergence, evolution and treatme...

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Literature Corpus work: bd3e8814-3736-5a50-b5cf-53a1dc0fbba9
DOI: 10.64898/2026.04.13.715606

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