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The Role of the Bone Marrow Microenvironment in the Pathogenesis of Acute Myeloid Leukemia

2026-06-09

Abstract excerpt

Acute myeloid leukemia (AML) develops within a bone marrow environment that influences leukemic stem-cell behavior, residual disease, and response to therapy. This review examines evidence that the marrow microenvironment is not only a site of leukemic growth, but can actively shape AML initiation, maintenance, and treatment resistance. Clinical observations such as donor cell leukemia after allogeneic transplanta...

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Literature Corpus work
38930871-6bd0-58db-8be0-17ef7152ddf6
DOI
10.20944/preprints202606.0716.v1
Open publication

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The Role of the Bone Marrow Microenvironment in the Pathogenesis of Acute Myeloid LeukemiaDOI 10.20944/preprints202606.0716.v1
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