Article

Cardiac progenitors auto-regulate second heart field cell fate via Wnt secretion

2021-01-31

Abstract excerpt

Proper heart formation requires coordinated development of two anatomically distinct groups of cells - the first and second heart fields (FHF and SHF). Given that congenital heart defects are often restricted to derivatives of the FHF or SHF, it is crucial to understand the mechanisms controlling their development. Wnt signaling has previously been implicated in SHF proliferation; however, the source of Wnts remai...

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Literature Corpus work: bd34c96c-e3e5-512e-a50f-ead93c3dc9a5
DOI: 10.1101/2021.01.31.428968

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