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Article

Live imaging of heart tube development in mouse reveals alternating phases of cardiac differentiation and morphogenesis

1 Dec 2017

Abstract excerpt

During vertebrate heart development, two progenitor populations, first and second heart fields (FHF, SHF), sequentially contribute to longitudinal subdivisions of the heart tube (HT), with the FHF contributing the left ventricle and part of the atria, and the SHF the rest of the heart. Here, we study the dynamics of cardiac differentiation and morphogenesis by tracking individual cells in live analysis of mouse...

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PMID: 29202929
DOI: 10.7554/elife.30668

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