Article
Developmental Heterogeneity of Foxp3⁺ Regulatory T Cells in the Orchestration of Metabolic Homeostasis
2025-05-09
Abstract excerpt
Regulatory T (Treg) cells were first identified through the observation that Foxp3 gene mutations in mice and humans can result in their dysfunction, leading to a catastrophic multi-organ autoimmune syndrome. Since then, it has become increasingly evident that Foxp3⁺ Treg cells serve functions extending well beyond dominant tolerance and the mere prevention of autoimmune pathology. Highlighting their pivotal role...
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Identifiers and source
- Literature Corpus work
- bd2c0e10-d1a8-5b3a-b319-884b969f3776
- DOI
- 10.20944/preprints202505.0281.v2