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Article

Regulatory T Cells in Autoimmunity and Cancer: A Duplicitous Lifestyle.

Frontiers in immunology - 1 Jan 2021

Hatzioannou Aikaterini, Boumpas Athina, Papadopoulou Miranta, Papafragkos Iosif, Varveri Athina, Alissafi Themis, Verginis Panayotis

Abstract excerpt

Regulatory T (Treg) cells, possess a strategic role in the maintenance of immune homeostasis, and their function has been closely linked to development of diverse pathologies including autoimmunity and cancer. Comprehensive studies in various disease contexts revealed an increased plasticity as a characteristic of Treg cells. Although Treg cell plasticity comes in various flavors, the major categories enclose the...

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Identifiers

PMID: 34539668
DOI: 10.3389/fimmu.2021.731947
PMCID: PMC8446642

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