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Revisiting regulatory T cells in type 1 diabetes

1 Aug 2012

Abstract excerpt

PURPOSE OF REVIEW: Regulatory T cells (Treg) maintain immune homeostasis and prevent autoimmune disease. This review summarizes the recent advances in Treg knowledge relevant to type 1 diabetes, focusing on Treg signature, antigen specificity and development and function in the face of inflammation. RECENT FINDINGS: Thymus-derived natural regulatory T cells (nTreg) programmed by the transcription factor forkhead...

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PMID: 22732485
DOI: 10.1097/med.0b013e328355a2d5

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