Article

Efficient Sequencing, Assembly, and Annotation of Human KIR Haplotypes

2020-07-13

Abstract excerpt

The homology, recombination, variation, and repetitive elements in the natural killer-cell immunoglobulin-like receptor (KIR) region has made full haplotype DNA interpretation impossible without physical separation of chromosomes. Here, we present a new approach using long-read sequencing to efficiently capture, sequence, and assemble diploid human KIR haplotypes. Sequences for capture probe design were derived fr...

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Literature Corpus work: 53d70581-371b-5daa-a74d-24a87adbe026
DOI: 10.1101/2020.07.12.199570

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