Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human and Rhesus Macaque KIR Haplotypes Defined by Their Transcriptomes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2018

Bruijnesteijn Jesse, van der Wiel Marit K H, Swelsen Wendy T N, Otting Nel, de Vos-Rouweler Annemiek J M, Elferink Diënne, Doxiadis Gaby G, Claas Frans H J, Lardy Neubury M, de Groot Natasja G, Bontrop Ronald E

Abstract excerpt

The killer-cell Ig-like receptors (KIRs) play a central role in the immune recognition in infection, pregnancy, and transplantation through their interactions with MHC class I molecules. KIR genes display abundant copy number variation as well as high levels of polymorphism. As a result, it is challenging to characterize this structurally dynamic region. KIR haplotypes have been analyzed in different species...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Copy Number Variations
Share to Gene Rearrangement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to High-Throughput Nucleotide Sequencing

Share to Histocompatibility Antigens Class I

Share to Macaca mulatta

Share to Receptors, KIR

Share to Transcriptome

Source

Identifiers

PMID: 29358278
DOI: 10.4049/jimmunol.1701480

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human and Rhesus Macaque KIR Haplotypes Defined by Their Transcriptomes.PMID 29358278Read ↗

Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques.Semantic proximity Read ↗

Complete characterization of killer Ig-like receptor (KIR) haplotypes in Mauritian cynomolgus macaques: novel insights into nonhuman primate KIR gene content and organization.Semantic proximity Read ↗

Unparalleled Rapid Evolution of KIR Genes in Rhesus and Cynomolgus Macaque Populations.Semantic proximity Read ↗

Characterization of rhesus macaque KIR genotypes and haplotypes.Semantic proximity Read ↗

Complete Genomic Assembly of Mauritian Cynomolgus Macaque Killer Ig-like Receptor and Natural Killer Group 2 Haplotypes.Semantic proximity Read ↗

Improved full-length killer cell immunoglobulin-like receptor transcript discovery in Mauritian cynomolgus macaquesSemantic proximity Read ↗

Revealing Complete Complex <i>KIR</i> Haplotypes Phased by Long-read Sequencing TechnologySemantic proximity Read ↗

Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates.Semantic proximity Read ↗

Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.Semantic proximity Read ↗

The mosaic of KIR haplotypes in rhesus macaques.Semantic proximity Read ↗

Deciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology.Semantic proximity Read ↗

HLA/MHC and KIR characterization in humans and non-human primates using Oxford Nanopore Technologies and Pacific Biosciences sequencing platforms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.