Article

Revealing Complete Complex <i>KIR</i> Haplotypes Phased by Long-read Sequencing Technology

2017-05-08

Abstract excerpt

The killer cell immunoglobulin-like receptor ( KIR ) region of human chromosome 19 contains up to sixteen genes for natural killer (NK) cell receptors that recognize human leukocyte antigen ( HLA )/peptide complexes and other ligands. The KIR proteins fulfill functional roles in infections, pregnancy, autoimmune diseases, and transplantation. However, their characterization remains a constant challenge. Not onl...

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Literature Corpus work: 5adb76b9-9e7d-56b8-955c-72ef802713fe
DOI: 10.1101/135426

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