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Localized oxygen control in a microfluidic osteochondral interface model recapitulates bone-cartilage crosstalk during osteoarthritis

2023-11-21

Abstract excerpt

Osteoarthritis (OA) is characterized by the dysregulation of the osteochondral interface between bone and cartilage. In vitro models that accurately mimic this interface hold great potential for understanding OA pathophysiology and screening therapeutic agents. Presently, research efforts have focused on emulating heterogeneity in structural and mechanical attributes of the extracellular matrix (ECM) at the osteo...

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Literature Corpus work
bd19cd96-4ee2-5130-ad04-f5912de8736a
DOI
10.1101/2023.11.20.567822
Open publication

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Localized oxygen control in a microfluidic osteochondral interface model recapitulates bone-cartilage crosstalk during osteoarthritisDOI 10.1101/2023.11.20.567822
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