Article

Biologically Driven In Vivo Occlusion Design Provides a Reliable Experimental Glaucoma Mouse Model

2024-01-23

Abstract excerpt

Fluid transport through the trabecular meshwork is a major regulator of intraocular pressure in healthy and glaucomatous eyes. Existing microbead occlusion models enable in vivo study of pressure-related glaucomatous pathology, but their long-term reliability is limited by inadequate bead-tissue interface design. Inspired by the graded porous architecture and fluid-transport function of the trabecular meshwork, we...

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Literature Corpus work: a7872403-fe50-510f-b1aa-a9f47da9d8a9
DOI: 10.1101/2024.01.18.576306

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