Article

Identification of the complete pathway for conversion of bilirubin to urobilinogen by human gut bacteria

2026-06-10

Abstract excerpt

Bilirubin, the predominant product of heme catabolism in mammals, enters the intestine via the hepatobiliary system and subsequently is metabolized by the gut microbiome. This process consumes bilirubin and generates multiple downstream derivatives, such as urobilinogen and stercobilinogen. Levels of bilirubin and its derivatives are associated with susceptibility to inflammatory and metabolic disorders, but the m...

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Literature Corpus work: bd1077e2-d4a5-5c3c-b044-c303938ecf4d
DOI: 10.64898/2026.06.10.731317

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